Résultats des appels à projets

2026

Innovation

  • Towards Stable « Naked » M3+ Tri-cations? Modelling and Experimental Studies | Alain CHAUMONT
  • Unraveling the complex mechanisms behind synthetic and biological nanosized materials formation using in situ liquid phase electron microscopy | Ovidiu ERSEN
  • Microplastics as Modifiers of Macrophage and Endothelial Function in Coronary Disease | Petra HELLWIG
  • Installation of Klymchenko Team Photoactive Materials and Bioimaging at the Institute Le Bel | Andrey KLYMCHENKO

ITI SysChem – Chimie des systèmes Complexes

  • The role of amino acid chirality in protein aging | Vladimir TORBEEV
  • Molecular devices based on a homochiral-heterochiral switch within trinuclear titanium(IV) self-assembled architectures | Pierre MOBIAN
  • Stitching pillar[5]arene derivatives to generate knotted structures | Jean-François NIERENGARTEN
  • CHIROGENS – Axially chiral viologens: electrochemical and photophysical enantioselective properties | Giulio RAGAZZON
  • Light-Activated Ru-Peptide Macrocycles Combining Targeting and Cytotoxicity | Irene REGENI

ITI SysChem – Emerging Investigators

  • Supramolecular control of charge transfer-enabled decarboxylative arylation (2026) | Nicolas KERN

Installation de nouvelles équipes de recherche à Strasbourg

  • Amino acid Regulation of Complex intracellular protein Networks | Xufeng XU

2025

Synergie locale

Permet l’achat de petits équipements en commun au service de la communauté :

  • NMR LED probe for in situ (supra)molecular characterization of light-responsive systems
  • FTIR microscope for structural studies of self-assemblies and dynamics of complex systems
  • Nanostructuring and handling nanomaterials
  • Mechanochemical functionalization of carbon electrode materials by high energy ball milling

Innovation

Finance les projets les plus innovants en chimie

  • Harnessing the Reactivity of « Super-sugars » in Novel Complexity-generating Cascade Reactions | Philippe COMAPIN
  • SAFERSUN: Towards a new methodology for assessing the photoallergic and phototoxic risks of chemicals in consumer products | Elena GIMENEZ-ARNAU
  • Crafting Chiral Complexity: A Synthetic Toolbox for Advanced Aza-Silaheterocycles | Frédéric LEROUX
  • Towards new antibiotics against anthrax and plague | Myriam SEEMANN

ITI SysChem – Chimie des systèmes Complexes

Soutient les projets les plus ambitieux dans ce domaine

  • Playing with – and learning from – motorized molecular toys (PLAYMOBIL) | Nicolas GIUSEPPONE
  • Developing a coupled nanodisc and electrochemical approach for the study of membrane proteins from the respiratory chain that catalyze oxygen reduction | Petra HELLWIG
  • Sigma-Bond Cleaving Strategies for Alkaloid Skeletal Editing | Amir HOVEYDA
  • Conformational complexity of the disordered N-terminal region in biological function of tumor suppressor p53 protein (« p53 complexity ») | Vladimir TORBEEV

ITI SysChem – Emerging Investigators

Soutient de jeunes chercheurs talentueux souhaitant développer leur indépendance dans le domaine de la chimie des systèmes complexes

  • Chiral metallosupramolecular architectures based on copper iodide nanoclusters as new earth-abundant metal-based CPL emitters | Aurélie GUENET

Installation de nouvelles équipes de recherche à Strasbourg

  • Organometallic Catalysis, Organic Synthesis and Health | Stefan CHASSAING
  • Chemistry of Photoresponsive Systems | Mayeul COLLOT
  • Functional Metal-Peptide Assemblies | Irene REGENI
  • Novel self-labeling proteins for chemical biology applications | Adrian SALIC

2024

Synergie locale

Permet l’achat de petits équipements en commun au service de la communauté :

  • Flow Cytometer | Dominique BONNET
  • Spectrofluorimeter | Frédéric LEROUX
  • Microfluidic plateform | Alain WAGNER

Innovation

Finance les projets les plus innovants en chimie

  • Exploring the Link between properties And StrucTure usIng a COmbinatorial library of elastin-like peptide | Fouzia BOULMEDAIS
  • Compact Biomacromolecule-Based Materials for Tissue Engineering | Benoit FRISCH
  • Visible-light induced activation of CF3-N-allenamides to promote [2+2]-cycloadditions | Laurence Miesch
  • Exploiting the IspG metalloenzyme using innovative molecular tools as a source of inspiration towards unprecedented antibacterial agents | Myriam SEEMANN

Chimie des systèmes Complexes

Soutient les projets les plus ambitieux dans ce domaine

  • Homoleptic N-heterocyclic carbene complexes of group 4 and 14 as effective alternative photosensitizers to heavy metals | Stéphane BELLEMIN-LAPONNAZ
  • CHIRALSPIN | Athanassios BOUDALIS
  • Supramolecular Chirogenesis: Switchable CD and CPL in Multi-Responsive Receptors | Valérie HEITZ
  • Polymeric nanoparticles with dynamic covalent chemistry for molecular recognition and fluorescence detection of neurotransmitters | Andrey KLYMCHENKO
  • Photo-electrocatalytic reduction of NOx catalyzed by polyoxometalates: mechanism insight, in situ characterization by differential electrochemical mass spectrometry | Laurent RUHLMANN
  • Enzyme-triggered membrane-less organelle formation with high protein partitioning | Pierre SCHAAF
  • Exploiting bacterial iron uptake pathways to deliver drugs: Investigation at the single cell level the expression of the bacterial iron uptake pathways | Isabelle SCHALK

Emerging Investigators

Soutient de jeunes chercheurs talentueux souhaitant développer leur indépendance dans le domaine de la chimie des systèmes complexes

  • Exploring spin communication in photogenerated triplet-radical systems based on naphthalene diimides | Rodrigo VARGAS JENTZSCH

2023

Synergie locale

Permet l’achat de petits équipements en commun au service de la communauté :

  • Differential refractive index detector for Size Exclusion Chromatography | Fouzia BOULMEDAIS
  • Electron microscopy platform for the operando study of nanomaterials | Ovidiu ERSEN

Innovation

Finance les projets les plus innovants en chimie

  • Mechanosynthesis and wafers-shaping of 2D and mixed 2D/3D hybrid perovskites for designing new X-Ray detector with improved stability and performance | Sylvie BEGIN-COLIN
  • Atropisomeric halogen bond donors | Xavier BUGAUT
  • Quantified Noncovalent Interactions for the Prediction of Reactivity | Jean-Pierre DJUKIC
  • Eight-shaped pillar[10]arene analogues: synthesis and incorporation in Solomon links | Jean-François NIERENGARTEN

Chimie des systèmes Complexes

Soutient les projets les plus ambitieux dans ce domaine

  • Broad-spectrum antiviral coatings using chemically modified graphene | Alberto BIANCO
  • Towards a molecular understanding of synaptic transduction | Marco CECCHINI
  • Symmetry and Chirality under Strong coupling | Thomas EBBESEN
  • Driving (supra)molecular systems Uphill with artificial molecular motors (DreamUp) | Nicolas GIUSEPPONE
  • Detection of the catalytic reaction in membrane proteins in biomimetic plasmonic nanopores by infrared microscopies | Petra HELLWIG
  • ATP-Fuelled Artificial non-equilibrium Systems (FASt) | Giulio RAGAZZON
  • Versatile Molecular Spin States for Spin-Qubits | Vincent ROBERT
  • Air stable radical ion pairs for supramolecular nanomaterials | Jean WEISS

Emerging Investigators

Soutient de jeunes chercheurs talentueux souhaitant développer leur indépendance dans le domaine de la chimie des systèmes complexes

  • Acridinium pi-dimer for Motion of Large Amplitude on Surfaces | Henri-Pierre JACQUOT

2022

Synergie locale

Permet l’achat de petits équipements en commun au service de la communauté :

  • NIR sensitive spectrofluorometer for accurate photophysical characterizations of NIR emitting dyes and particles | Luc LEBEAU
  • Upgrade of the Cronenbourg NMR Core Facility research spectrometer magnet | Frédéric LEROUX

Innovation

Finance les projets les plus innovants en chimie

  • Anisotropic properties of complex self-assembled nanocellulose-based materials | Olivier FELIX
  • SN2′-Reactions on Polyfluorinated N-Allenamides to generate 1,1-Difluoroalkene Carbonyl Mimics | Laurence MIESCH
  • Hidden treasure of λ3-chloranes: new horizon for the synthetic chemistry | Joanna WENCEL-DELORD

Chimie des systèmes Complexes

Soutient les projets les plus ambitieux dans ce domaine

  • Structural analysis of peptide-lipid nanoparticles with a range of therapeutic activities | Burkard BECHINGER
  • Prebiotic ecosystems of synergistic early cells | Claudia BONFIO
  • Enantioselective beta-Arylation of Alcohols via the Productive Merger of Relay Ru/Rh-Catalysis and Dynamic Kinetic Resolution of Transient alpha-Aryl Aldehydes | Pawel DYDIO
  • Understanding the importance of thiols for biological active copper-ligand complexes | Peter FALLER
  • Strong-CPL: enhancing circularly polarized luminescence via strong coupling | Cyriaque GENET
  • Innovative Development of Light-gated Piezo Channels with Chemical Photoswitches | Thomas GRUTTER
  • Molecular-engineered biradicals as two-qubit gates (QBIRAD) | Mario RUBEN
  • Harnessing chemical complexity in high-performance flexible rechargeable Zn-ion batteries (ComplexZnBatt) | Paolo SAMORI
  • Micropatterning Controlled By Enzyme-Assisted Self-Assembly Through Liesegang-like Processes | Pierre SCHAAF
  • Protein complex with rotaxane polypeptide chain topology: design, synthesis, biophysical properties and applications in vivo | Vladimir TORBEEV

Emerging Investigators

Soutient de jeunes chercheurs talentueux souhaitant développer leur indépendance dans le domaine de la chimie des systèmes complexes

  • Self-Assembling De Novo Peptides as Innovative Crystallization Scaffold | Vincent LEBRUN

Installation de nouvelles équipes de recherche à Strasbourg

  • Enantioselective Oxidative Aromatization | Xavier BUGAUT

2021

Synergie locale

Permet l’achat de petits équipements en commun au service de la communauté : aucun projet sélectionné

Innovation

Finance les projets les plus innovants en chimie

  • Lignin-based covalent adaptative networks (LigniCAN) | Luc AVEROUS
  • Design of self-assembled THermoresponsive macromolecular nanostructures for the delivery of Essential OilS (THEOS) | Fouzia BOULMEDAIS
  • Development of a fully catalytic method of enantioselective difluoromethylation towards difluoromethylated bioisosteres (DiFluChir) | Frédéric LEROUX
  • Site-specific monitoring of RNA G-quadruplex dynamics and interactions with an isomorphic fluorescent nucleoside analogue | Yves MELY
  • Transition metal/oxide heterostructures for electrocatalysis of oxidation of complex fuels | Elena SAVINOVA

Chimie des systèmes Complexes

Soutient les projets les plus ambitieux dans ce domaine

  • Case studies of nonlinear effects in asymmetric catalysis: elucidating principals and applications | Stéphane BELLEMIN-LAPONNAZ
  • Photothermal therapy mediated by multifunctional 2D materials | Alberto BIANCO
  • Complex out-of-equiIibrium molecular rotors | Nicolas GIUSEPPONE
  • ATP-controlled erasing and rewriting in macromolecular information networks | Jean-François LUTZ
  • Controlling Regioselectivity through Vibrational Strong Coupling | Joseph MORAN
  • SUPRAmolecularly engineered chemical SENSors based on metal nanoparticles for detection of metal ions (SUPRASENS) | Paolo SAMORI

Emerging Investigators

Soutient de jeunes chercheurs talentueux souhaitant développer leur indépendance dans le domaine de la chimie des systèmes complexes

  • Pi-Anion Interactions as a Design Principle for Organometallic Catalysts | David LEBOEUF
  • 89Zr-labeled radioimmunoconjugates with bispidine ligands | Aline NONAT

Installation de nouvelles équipes de recherche à Strasbourg

  • Towards the emergence of modern cells | Claudia BONFIO
  • Assembly of KInetically-trapped Nanomaterials (AKIN) | Giulio RAGAZZON

2020

Synergie locale

Permet l’achat de petits équipements en commun au service de la communauté

  • Ultraclean van der Waals Heterostructures | Bernard DOUDIN
  • Liquide-Chromatography Coupled with Mass Spectrometry for Sensitive and Accurate Peptide Analysis | Peter FALLER
  • State of the Art Computational Tools for a better understanding of experimental results | Marc HENRY
  • Improvement of the Cronenbourg NMR facility | Frédéric LEROUX

Innovation

Finance les projets les plus innovants en chimie

  • A Unified Approach to Nogalamycin-Related Anthracyclines through Catalytic Hydrogen Atom Transfer-initiated Reactions | Philippe COMPAIN
  • Ultrafast spectroscopy of conical intersections in biomimetic photoswitches | Stefan HAACKE
  • In situ chemical reactivity of p-phenylenediamine, a major skin sensitizer, in reconstructed human epidermis: A quantititative HRMAS NMR approach | Jean-Pierre LEPOITTEVIN
  • Atomic-scale magnetometry using a single-molecule spin sensor | Laurent LIMOT

Chimie des systèmes complexes

Soutient les projets les plus ambitieux dans ce domaine

  • Enantio- and Chemoselective Supramolecular Catalysis in Water using Metal Nanoparticles Stabilized with SPO-Capped Cyclodextrins | Dominique ARMSPACH
  • Allosterically controlled synthesis and properties of [2]rotaxanes | Valérie HEITZ
  • Giant molecular machines | Jean-François NIERENGARTEN
  • Deciphering protein-protein interactions involving intrinsically disordered proteins | Vladimir TORBEEV
  • Organo- & MetalloCatalysis towards C-Glycosides | Patrick PALE
  • New strategy for gene therapy in the lung | Luc LEBEAU
  • Structural foundations of peptide-based membrane mesophases with much enhanced biological activities | Burkhard BECHINGER
  • Fighting antibiotic resistance by targeting the bacterial LytB enzyme | Myriam SEEMANN

Emerging Investigators

Soutient de jeunes chercheurs talentueux souhaitant développer leur indépendance dans le domaine de la chimie des systèmes complexes

  • Heterogeneous Reusable Catalysts bearing Gold Nanoparticules for C-Heteroatome Bond Forming Reactions | Gaelle BLOND
  • Flow chemistry for prebiotic complex systems | Kamila MUCHOWSKA
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